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Centrifugal Therapeutic Plasma Exchange (cTPE)
Providing Nephrologists With a Solution That Adapts to Their Needs
Overview How it Works Webinars Videos Resources
PLASMA EXCHANGE TECHNOLOGY CAN MAKE A DIFFERENCE

The therapeutic plasma exchange (TPE) technology that you choose can make all the difference in finding a solution that adapts to your needs and improves patient experience. Discover cTPE on Spectra Optia.

HOW cTPE WORKS
Spectra Optia uses differences in the specific gravity and sedimentation velocity of blood cells and plasma to separate specific blood components.

With continuous flow centrifugation, blood is continuously added into the centrifuge; blood cells are separated from plasma, mixed with replacement fluid and returned to the patient.

DISCLAIMER: This graphic is intended to be a high-level representation of an apheresis procedure and therefore does not cover all steps. For a detailed description please contact Terumo BCT.

With its cTPE technology, Spectra Optia provides clinicians with a solution that adapts to their needs and improves the patient experience.



Spectra Optia® Apheresis System offers:

EASE OF USE →
EFFICIENT PROCEDURE TIME →
MULTIPLE VENOUS ACCESS OPTIONS →
DEMONSTRATED DEPENDABILITY →

EASE OF USE

Spectra Optia simplifies the operator’s work and makes it easy to complete procedures.

  • The intuitive touch screen guides the operator through an eight-step TPE procedure
  • The operator can safely pause the procedure at any point without losing procedure information
  • The operator can access automated calculations of parameters, such as:
    • Total blood volume
    • Anticoagulant infusion rate
    • Plasma volume

EFFICIENT PROCEDURE TIME

Enhance Operator Comfort and Patient Safety

Spectra Optia provides an efficient TPE procedure time while maintaining procedural safety limits, allowing operators to maximize the time with patients and improve the patient experience.

Flow Rates

Flow rates up to 142 mL/min can be used while maintaining procedure efficiency.4 For smaller patients, a flow rate of 5 mL/min or less can be used. This adapts to the operator’s needs and the patient’s condition.

MULTIPLE VENOUS ACCESS OPTIONS

When tailoring a procedure for each patient, operators appreciate the flexibility of the multiple venous access options that can be used with the Spectra Optia system, including:

  • Peripheral venous access with single- or dual-needle options
  • Other venous access options, such as:
    • Central venous catheter
    • Arteriovenous (AV) fistula or AV graft
    • Implanted ports

DEMONSTRATED DEPENDABILITY

The reliability of Spectra Optia offers peace of mind for physicians and operators alike.

  • No clotting event resulting in premature ending of a TPE procedure or obligated use of an additional tubing set has ever been reported in peer-reviewed literature on Spectra Optia.
  • The operator can depend on Spectra Optia to provide accurate anticoagulant management.






VIDEOS

Hear From Your Peers

See how David Ward, MD, Medical Director, Apheresis Program, University of California San Diego (UCSD), La Jolla, California uses cTPE on Spectra Optia.




RESOURCES

Recent Literature

A Randomized Crossover Study Comparing Membrane and Centrifugal Therapeutic Plasma Exchange Procedures

By Peter Kes, Michiel Etienne Janssens, Nikolina Basic-Jukic and Milica Kljak

Download Article

Membrane Versus Centrifuge-Based Therapeutic Plasma Exchange: A Randomized Prospective Crossover Study

By Carsten Hafer, Paulina Golla, Marion Gericke, Gabriele Eden, Gernot Beutel, Julius J. Schmidt, Bernhard M. W. Schmidt, Stef De Reys and Jan T. Kielstein

Download Article

Membrane and Centrifugal Therapeutic Plasma Exchange: Practical Difficulties in Anticoagulating the Extracorporeal Circuit

By B. Puppe and E.J. Kingdon

Download Article




Spectra Optia Materials





References

1Timing study based on internal laboratory time studies using highly trained operators. Time is approximate and results may vary depending on operator experience. Data on file.

2Kes P, et al. A randomized crossover study comparing membrane and centrifugal therapeutic plasma exchange procedures. Transfusion. 2016;56(12):2065-3072.

3Data on file; encompasses data from more than 40,000 procedures.

4Procedures can be defined as being efficient in terms of the following:

  • Plasma removal efficiency (PRE)
  • Fluid balance
  • Anticoagulant management
  • Run targets
  • Pump flow rate accuracy

Other References

Puppe B, Kingdon EJ. Membrane and centrifugal therapeutic plasma exchange: practical difficulties in anticoagulating the extracorporeal circuit. Clin Kidney J. 2014;7(2):201-205.

Hafer C, Golla P, Gericke M, et al. Membrane versus centrifuge-based therapeutic plasma exchange: a randomized prospective crossover study. Intl Urol and Nephrol. 2016;48(1):133-138.

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