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Terumo BCT – Cell and Gene Therapy Automation Solutions
Cell Therapy Technologies
Automation News & Webinars IQ/OQ Research Contact Us
Choosing the right automation partner makes all the difference when you need to optimize your process. We offer over 40 years of expertise and a range of modular automated solutions to streamline and simplify the most complex parts of your process.

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Integrate automation into your process.

See how adopting automation early in your cell production efforts can help you advance the development of novel therapies for the patients who need them. Maintain the integrity of your work as it progresses into later phases of development by streamlining and simplifying the most complex parts of your process — from cell collections to cell expansion to fill and finish.

Enable reproducible, scalable processes

When comparing mesenchymal stromal cell production in flasks versus the Quantum® Cell Expansion System, automation showed an 88% reduction in harvest time and labor hours.2

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Performance varies by user and is dependent on customer processes and materials.

Increase control over variability

  • Maintain cell viability of greater than 95% of the inlet cell viability throughout final formulation with the Finia® Fill and Finish System.
  • Maintain uniformity of cell concentrations to within 5% on all final product bags and a QC bag with Finia.

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Performance varies by user and is dependent on customer processes and materials.

Reduce variables in the work path and improve efficiency

Use of an automated bioreactor closed system has been shown to increase yields and reduce growing times for a variety of cell types. In one report, City of Hope generated a GMP-grade lot of clinically viable neural stem cells within nine days with Quantum, compared with six weeks using cell factories.1

LEARN MORE

Performance varies by user and is dependent on customer processes and materials.

Reduce open events with a closed cell culture environment

The closed environment of the bioreactor remains intact during the cell culture process, eliminating open events and hands-on tasks associated with manual flask-based culture. One study from Baylor College of Medicine Center for Cell and Gene Therapy showed a 99.8% reduction in open events when using Quantum compared to an equivalent flask-based process.2

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Performance varies by user and is dependent on customer processes and materials.

Expand multiple cell types with Quantum

  • Mesenchymal stem cells (MSCs)
  • T cells
  • Fibroblasts
  • Dendritic cells
  • HEK 293T (for viral vector production)
LEARN MORE


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Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

Cell Processing System

Currently under development.

This functionally closed system is designed to wash and concentrate cells.

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More
collect-icon

Spectra Optia® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

Learn More

COBE® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

Learn More

Quantum® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

Learn More

FINIA® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

Learn More

Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

Learn More
Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

Learn More
Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

Learn More

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On-Demand Webinars


A Lens on the Final Formulation and Fill & Finish Process: Considerations for Process Automation and Device Development
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Real-World Insights Into Automated Solutions for Cell and Gene Therapy Bioprocessing
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Clinical Application of Adipose-Derived Stromal Cells in Ischemic Heart Disease
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Serendipity – To Find a Process While Looking for a Product
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You are not in this alone.

We believe that service, support and training go hand in hand with innovation. We partner with customers at multiple stages of the development process — from cell collection to cell expansion to final formulation — working together to achieve successful outcomes. Look to Terumo Blood and Cell Technologies for the following services:

Read the research.





GMP Production and Scale-Up of Adherent Neural Stem Cells With a Quantum Cell Expansion System

This report shares how City of Hope generated a GMP-grade lot of clinically viable neural stem cells within nine days with Quantum, compared to six weeks using cell factories.

DOWNLOAD


Large-Scale Production of Lentiviral Vector in a Closed System Hollow Fiber Bioreactor

Learn how researchers at the University of California, Davis developed a method employing a hollow-fiber bioreactor to generate a large-scale system method for the manufacturing of clinical-grade lentiviral vectors suitable for the generation of induced pluripotent stem cells.

DOWNLOAD


Characterization and Cost-Benefit Analysis of Automated Bioreactor Expanded Mesenchymal Stem Cells for Clinical Applications

See how researchers at the Mayo Clinic used an automated bioreactor to manufacture MSCs that were physically and functionally equivalent to the MSCs manufactured by manual flask method.

DOWNLOAD









1Data from one report: Tirughana R, Metz MZ, Li Z, et al. GMP production and scale-up of adherent stem cells with a Quantum Cell Expansion System. Mol Ther Methods Clin Dev. 2018;10:48-56.

2Hanley P, Mei Z, Durett A, et al. Efficient manufacturing of therapeutic mesenchymal stromal cells with the use of the Quantum Cell Expansion System. Cytotherapy. 2014;16(8):1048-1058.





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