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Terumo BCT – Cell and Gene Therapy Automation Solutions

Cell Therapy Technologies

Automation

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Automating Your Process Puts Next-Generation Cell and Gene Therapies Within Reach

Choosing the right automation partner makes all the difference when you need to optimize your process. We offer over 40 years of expertise and a range of modular automated solutions to streamline and simplify the most complex parts of your process.

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Integrate automation into your process.

See how adopting automation early in your cell production efforts can help you advance the development of novel therapies for the patients who need them. Maintain the integrity of your work as it progresses into later phases of development by streamlining and simplifying the most complex parts of your process — from cell collections to cell expansion to fill and finish.

Enable reproducible, scalable processes

When comparing mesenchymal stromal cell production in flasks versus the Quantum^® Cell Expansion System, automation showed an 88% reduction in harvest time and labor hours.²

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Performance varies by user and is dependent on customer processes and materials.

Increase control over variability

Maintain cell viability of greater than 95% of the inlet cell viability throughout final formulation with the Finia^® Fill and Finish System.
Maintain uniformity of cell concentrations to within 5% on all final product bags and a QC bag with Finia.

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Performance varies by user and is dependent on customer processes and materials.

Reduce variables in the work path and improve efficiency

Use of an automated bioreactor closed system has been shown to increase yields and reduce growing times for a variety of cell types. In one report, City of Hope generated a GMP-grade lot of clinically viable neural stem cells within nine days with Quantum, compared with six weeks using cell factories.¹

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Performance varies by user and is dependent on customer processes and materials.

Reduce open events with a closed cell culture environment

The closed environment of the bioreactor remains intact during the cell culture process, eliminating open events and hands-on tasks associated with manual flask-based culture. One study from Baylor College of Medicine Center for Cell and Gene Therapy showed a 99.8% reduction in open events when using Quantum compared to an equivalent flask-based process.²

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Performance varies by user and is dependent on customer processes and materials.

Expand multiple cell types with Quantum

Mesenchymal stem cells (MSCs)
T cells
Fibroblasts
Dendritic cells
HEK 293T (for viral vector production)

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Spectra Optia^® Apheresis System

A cell collection platform that provides an automated and flexible method for collecting MNCs.

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COBE^® 2991 CELL PROCESSOR

A variety of cell processing applications have earned it a reputation for reliability, ease of use, instrument consistency, disposable set performance and multiapplication flexibility.

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Quantum^® Cell Expansion System

An automated cell culture platform that has been shown to sustain cellular modification processes in the cultured cells through the use of transduction and transfection.

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Quantum^® Cell Expansion System

An automated cell culture platform that has been proven effective in the consistent expansion of suspension cells, adherent cells, viral vectors and exosomes.

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FINIA^® Fill and Finish System

The first device of its kind to automate final formulation and the fill and finish step. Finia is designed to automatically formulate, aliquot, cool, remove air and package cell and gene therapy products to enable cryopreservation.

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Bioprocessing Welders

Dependable sterile connection devices to support final product quality and operational efficiency throughout your process.

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Workflow-centered software that connects your cell transplant/cell therapy teams and systems across the patient pathway and centrally manages patient, product and process data.

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Spectra Optia Cell Collection Services led by data analytics specialists who can help you unlock your collection data and identify areas for improvement.

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