Patients treated early with TPE required less mechanical ventilation, and hospitalisation time was decreased.
–Hund et al., 1993
The Spectra Optia system is the first therapeutic apheresis system with an indication to treat GBS, and Spectra Optia plasma exchange is recommended as a first-line therapy. Using plasma exchange on the Spectra Optia system to treat patients with GBS results in a rapid clinical response and a fast road to recovery in majority of patients.
Class I (Level A for severe GBS)
Category I (Grade 1A) and Category III (Grade 2C)
1Cortese I, et al. Neurology. 2011; 76:294-300. 2Schwartz J, et al. J Clin Apher. 2016; 31(3):149-162. 3Elovaara I, et al. Eur J Neurol. 2008; 15:893-908.
When patients are progressing quickly, a decisive first response is critical. The longer treatment is delayed, the less likely it is that a patient will achieve optimal results. Studies show that GBS patients who receive plasma exchange therapy experience faster response and recovery compared to those receiving only supportive care. (Chevret S et al., 2017)
In addition to a rapid overall recovery time, GBS patients receiving plasma exchange treatment showed the following: (Chevret S et al., 2017)
One or more disability-grade improvements after 4 weeks
Decreased time on a ventilator
Improved functional abilities (for example, faster time to unaided walking and significantly improved grip strength 3 weeks after first plasma exchange)
Increased probability of full muscle strength recovery and decreased probability of severe sequelae and relapse at 1 year
Possible patient reactions
Reactions to transfused blood products can include1
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1AABB (ed.), et al., Circular of Information for the Use of Human Blood and Blood Components. 2006, tenth edition, Council of Europe Publishing, Seattle, WA.
2American Society for Apheresis. Guidelines for therapeutic apheresis clinical privileges. J Clin Apher. 2007;22(3):181-182.
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